Raw material particle size and morphology are critical characteristics overlooked in processing. Milling and micronizing can be a crucial first or last step in product development. Surface area and particle shape are key facts that must be taken into consideration.
The process of reducing the average diameter of a solid material's particles to improve its ability to dissolve in a formulation. Milling is a typical technique that involves spinning spheres in a drum that collide with the particles, making them smaller in diameter.